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Epigenome association study of fathers’ preconception body silhouette, provide mechanistic insight into how epigenetic inheritance impact his children’s obesity, asthma and lung function.Research published in Nature Communications Biology is the first human study to reveal the biological mechanism behind the impact of fathers’ early teenage obesity on their children. https://www.nature.com/articles/s42003-025-08121-9. |
Father’s adolescent body silhouette is associated with offspring asthma, lung function and BMI through DNA methylation
People whose fathers were overweight as teenagers had epigenetic markers associated with asthma, obesity and low lung function.