This study encompassed the abnormal changes in the genes caused by the SARS-CoV-2 and pointed out the significant genes affected by this novel virus with the complete metabolic pathways. It is found that cytokines such as IL2, IL7, and IL10 play an essential role in maximizing the severity of SARS-CoV-2. The ACE2 enzyme and VEGF affect the brain and cause inflammation in the central nervous system. The purpose of this review is to bring down the seriousness of SARS-CoV-2. It is better to target the cytokines for the possible results, and for treating the SARS-CoV-2 neurological symptoms, VEGF is a probable therapeutic target in reducing inflammation in the brain. Therefore, this review could benefit not only from this virus's therapeutic basis but also for clinical observation, identification, and mediation of SARS-CoV-2 infection in the future.
Identification of selected genes associated with the SARS-CoV-2: a therapeutic approach and disease severity
SARS-CoV-2 is an extremely infectious and transmissible virus that develops severe conditions like respiratory syndrome, high blood pressure and weakens the immune system. Coronavirus falls under the Coronaviridae family and the Beta coronavirus genus.