Our prospective study aimed to investigate antimicrobial susceptibility patterns, risk factors, and their impact on mortality in cancer patients. We enrolled 440 patients and analyzed 541 isolates, revealing a staggering 48.01% multidrug resistance (MDR) and 29.76% extensive drug resistance (XDR) rates.
Key Findings:
- Risk factors like surgery, chemotherapy, and antibiotic exposure increased the likelihood of MDR and XDR infections.
- Longer hospital stays and higher mortality rates were associated with MDR and XDR infections.
- Cancer recurrence, sepsis, and low MASCC scores were identified as risk factors for mortality.
Our study highlights the urgent need for personalized interventions in cancer patients, including targeted infection control measures, judicious antibiotic use, and enhanced surveillance. By sharing our findings, we hope to spark a conversation within the scientific community, encouraging collaborative efforts to combat antimicrobial resistance.