Toxic effects of polystyrene nanoplastics on MDA‑MB‑231 breast cancer and HFF‑2 normal fibroblast cells: viability, cell death, cell cycle and antioxidant enzyme activity

According to previous research, nanoplastics have been identified in water, soil, air, and sludge. Polystyrene is one of the most common plastics used in different industries. Polystyrene is made of styrene monomers.

PS-NH2 exhibits dose- and size-dependent cytotoxicity in MDA-MB-231 and HFF-2 cells. Smaller particle

sizes and higher concentrations of PS-NH2 enhance oxidative stress, leading to apoptosis and cell cycle arrest.