Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
How amygdala plays in obsessive-compulsive disorder: Magnetic resonance imaging reveals a specific role of amygdala subregions
Accumulating evidence show amygdala involved in obsessive-compulsive disorder(OCD). Prior studies typically examined the amygdala as a homogeneous structure. Here we segment the amygdala with connectivity-based parcellation approach and suggest disorganized amygdala subregional networks in OCD.
Circular Vectors better than plasmids for RNA guide delivery and expression in cell culture experiments
We have developed an efficient, fully synthetic method and protocol called the Circular Vector method, which enables the production of circularized DNA containing expression elements that are ready for transfection in as little as 3 hours, thereby eliminating all bacterial cloning steps.
The connective tissue protein 'ADAMTSL3' is crucial for heart function
A new study reveals essential role of ADAMTSL3, an extracellular protein of unknown function, in maintaining cardiac structure and function in the failing heart. By regulating a central heart failure signalling pathway, ADAMTSL3 emerges as a potential therapeutic target for this deadly syndrome.
