Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Divalent and multivalent cations control liquid-like assembly of poly(ADP-ribosyl)ated PARP1 into multimolecular associates in vitro
We explain the role of poly(ADP-ribose) and biology relevant cations in the formation of condensates and points to the direct involvement of poly(ADP-ribosyl)ated PARP1 in the regulation of DNA repair via condensate formation.
Membrane topography variations cause apparent protein clustering
Apparent clustering of membrane proteins occurs upon failing to account for membrane topography variations. This we demonstrate and present a remedy for. Our data suggest that the high incidence of clustering reported misrepresents biology of consequence for our conceptional understanding.
How to reduce the negative impacts of artificial light at night on flying insects
We are reporting on our inter- and trans-disciplinary applied research that aimed to reduce negative effects of light pollution on nocturnal insects
Exploring New Frontiers in Antifungal Therapy: The Essential Role of Vitamin B5 Metabolism
Fungal infections pose a significant global health threat, especially with the alarming rise in drug-resistant strains. Our study, published in Communications Biology, delves into groundbreaking research that could pave the way for novel therapeutic strategies against these pathogens.
Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems
Phosphorelay systems found in fungi contain several hybrid histidine kinases that transfer phosphoryl groups to the same His-phosphotransferase. This many-to-one mechanism is promoted through a low affinity for interaction and a transient phosphorylation.
