An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Circular Vectors better than plasmids for RNA guide delivery and expression in cell culture experiments
We have developed an efficient, fully synthetic method and protocol called the Circular Vector method, which enables the production of circularized DNA containing expression elements that are ready for transfection in as little as 3 hours, thereby eliminating all bacterial cloning steps.
A new study reveals essential role of ADAMTSL3, an extracellular protein of unknown function, in maintaining cardiac structure and function in the failing heart. By regulating a central heart failure signalling pathway, ADAMTSL3 emerges as a potential therapeutic target for this deadly syndrome.
Citizen science data reveal that climate, currents and species traits all contribute to the early stages of marine species redistributions