Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Plasminogen-Apple-Nematode (PAN) domain: A new target to modulate the HGF/c-MET signaling in cancers.
Our newly published paper suggests that four cysteine residues at the core of the HGF PAN domain are essential for its binding with the proto-oncogenic receptor c-MET and the subsequent activation of the downstream signaling cascade. Debjani Pal, Kuntal De, and Wellington Muchero.
Exploiting the temporal dimension of hydrogen-deuterium exchange mass-spectrometry to localise protein-protein interactions
Our paper describes a method to more accurately extract structural information about protein-protein interactions from hydrogen-deuterium exchange mass spectrometry (HDX-MS).
Early anesthesia using ketamine may affect addictive behavior later in life
Although anesthesia-induced neurotoxicity has received significant research interest, it is important to note that it was first identified in animals without direct clinical evidence, making it difficult to speculate how this might manifest in children.
The story behind AMAISE (A Machine learning Approach to Index-free Sequence Enrichment)
Why we decided to develop a machine learning-based tool to computationally remove host sequences from samples
