Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
A chromosome-wide view of an exceptionally diverse helminth
By resolving the chromosomes of the gastrointestinal parasitic nematode, Haemonchus contortus, we have provided unique insights into the chromosomal evolution and genome-wide diversity of this globally important pathogen.
B Cells: At the intersection of enhanced responses to immunotherapy treatments
B cells have strong clinical significance as drivers of antitumor immunity in triple negative breast cancer. While B cells are known to enhance T cell-mediated tumor killing, we have also uncovered a potential regulatory function, in which they suppress myeloid-derived suppressor cells.
Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
This study identified 43 novel non-HLA loci associated with Type 1 diabetes (T1D) in patients harboring low GRS.