Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Navigating New Territory in a Small Lab
The journey behind our recent paper was a long one, filled with hurdles and unexpected turns that we learned to navigate along the way. Working from a small lab with limited resources, we embarked on a project that introduced us to the complex and evolving field of biomolecular phase separation.
Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization
Activating the mevalonate (MVA) pathway increases bladder cancer (BLCA) spread. High MVA enzyme levels predict worse outcomes. Drugs like zoledronic acid or simvastatin blocking this pathway reduce cancer cell migration by affecting the protein RhoB. Targeting the MVA pathway could help treat BLCA.
Unveiling the 'hidden' effects of subclinical infection - a movement ecology perspective
Parasitism is one of the most ubiquitous strategies across ecosystems. Yet, wildlife researchers often assume animals are healthy and performing optimally. In reality, many carry 'hidden' infections with masked symptoms that nevertheless affect movement capacity, potentially impacting host fitness.
Deep Learning-based Fragmentation Approach for Single-Molecule Fluorescence Event Identification
By adapting user-defined criteria, DEBRIS is capable of accurately categorizing and analyzing four distinct types of single-molecule fluorescence events using a single trained AI model.
