Leukemia
This journal publishes high quality, peer reviewed research that covers all aspects of the research and treatment of leukemia and allied diseases. Topics of interest include oncogenes, growth factors, stem cells, leukemia genomics, cell cycle, signal transduction and molecular targets for therapy.
NGS-based IGHV SHM analysis in CLL
The most challenging part of NGS-based IGHV analysis in CLL concerns the interpretation of the findings rather than the analysis per se.
ERIC and EuroClonality-NGS are working hard on addressing open issues and on standardization. See Davi et al., Leukemia 2020, doi: 10.1038/s41375-020-0923-9.
The invisible enemies: COVID-19 and Multiple Myeloma
Binod Dhakal, Anita D'Souza, Saurabh Chhabra, Parameswaran Hari,
Medical College of Wisconsin
Milwaukee, WI, USA
Targeting dysfunction of microRNA in MLL leukemia
In our latest manuscript in Leukemia, we describe a putative additional mechanism for MYC deregulation downstream of MLL. We further demonstrate that IRAK1/4 inhibitor might improve the efficacy of BET inhibitor through synergistically downregulating MYC in MLL leukemias.
