Proteasome-independent K63 polyubiquitination selectively regulates ATP levels and proteasome activity during fear memory formation in the female amygdala
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus; Boutros et al. 2023
“What causes Alzheimer’s disease?” This question lies at the heart of aging research. It has remained elusive since an “unusual disease of the cerebral cortex” was first described by Dr. Alois Alzheimer in 1906.