MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus; Boutros et al. 2023
“What causes Alzheimer’s disease?” This question lies at the heart of aging research. It has remained elusive since an “unusual disease of the cerebral cortex” was first described by Dr. Alois Alzheimer in 1906.
Neural substrates underlying stress susceptibility in virgin female mice confer stress-coping in mother mice
Disruptions in caregiving can lead to profound impacts on emotional and physical development in young across species, including humans. Here, we examine the divergent impact of stress on mouse caregiving neural circuitry in alloparental and maternal females.