Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.
Streamlining DNA Mutation Detection: A Breakthrough with Phosphorothioated DNA-guided Endonuclease Excision
Detecting low-frequency DNA mutations remains a daunting task due to the background noise caused by wild-type (WT) DNA. In this article, we present a recent breakthrough that simplifies DNA mutation detection by eliminating WT DNA background using phosphorothioated DNA-guided endonuclease excision.
