Nature Biotechnology
A monthly journal covering the science and business of biotechnology, with new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences.
Advancing Health Equity for Medical Devices
Proposed reforms to the FDA's Breakthrough Medical Devices program provide an opportunity to examine challenges and potential solutions for addressing health disparities in medical device development.
Measuring the impact of chromatin context on transcription factor binding affinities
We have designed a new method, Binding Affinities to Native Chromatin by sequencing (BANC-seq), to determine transcription factor concentrations needed to bind regulatory elements in the genome. We show that chromatin context and DNA accessibility are key regulators of transcription factor binding.
