Nature Biotechnology
A monthly journal covering the science and business of biotechnology, with new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences.
European patent protection for medical uses of known products and drug repurposing
Obtaining European patent protection for medical uses of known products is not a key factor limiting repurposing activity.
AAV- homologous recombination based therapeutics
Recombinant AAV vectors are becoming more popular for therapeutic genome editing. We describe a clinically relevant approach to enhance insertion a therapeutic sequence into almost any site in the host genome.
Developing a therapeutic RNA base editing platform
Wave was founded on the idea that controlling backbone stereochemistry has potential to improve chemically modified oligonucleotide therapeutics. We now report a stereopure RNA base editing platform, adding a new modality that can help us deliver transformational therapies for patients .
Sparse deconvolution: one decisive step into computational fluorescence superresolution
We stumble upon an iterative optimization of fluorescence images followed by the RL deconvolution using the spatiotemporal continuity and sparsity prior knowledge. This Sparse deconvolution algorithm can extend spatial resolutions of fluorescence microscopes beyond their hardware constraints.
Mapping the European Patent Landscape for Medical Uses of Known Products
European Patent Office (EPO) data show an increasing number of patents for new medical uses of known products
