Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Behind the paper blog post
In our Nature Communications paper on “Hardening in Au-Ag Nanoboxes from Stacking Fault-Dislocation Interactions”, we use colloidal synthesis techniques to make metallic nanoboxes of ~100 nm in size, and study their intriguing mechanical behavior using in-situ SEM, in-situ TEM and MD simulations.
Engineering “smart” co-cultures
Synthetic biologists are increasingly using co-culture systems, but tools to control the composition of subpopulations are lacking. We designed a co-culture with signal translator and growth controller modules where culture composition autonomously adjusts in response to the AI-2 QS molecule.
The adverse effects of clonal hematopoiesis in multiple myeloma
Tarek H. Mouhieddine, MD
Synthesis and versatile reactivity of scandium phosphinophosphinidene complexes
Due to the energy mismatching between the frontier orbitals of rare-earth metal and ligand atom, the rare-earth metal-phosphorus multiple bonds are very unstable. This Behind introduces our group’s struggling trip to the first rare-earth monometallic phosphinidene complex during the past 10 years.
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Ewing sarcoma is a pediatric cancer characterized by chimeric EWSR1-ETS fusion oncogenes (in 85% EWSR1-FLI1). In our recent study, we showed that EWSR1-FLI1 hijacks the developmental transcription factor SOX6, which contributes to tumor growth but also increases sensitivity toward oxidative stress.