Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
PTMGPT2: An Interpretable Protein Language Model for Enhanced Post-Translational Modification Prediction
PTMGPT2 uses GPT-based architecture and prompt-based fine-tuning to predict post-translational modifications. It outperforms existing methods across 19 PTM types, offering interpretability and mutation analysis. This advances the understanding of protein function and disease research.
Directional long-distance electron transfer from reduced to oxidized zones in the subsurface
This study reveals a directional long-distance electron transfer chain from reduced to oxidized zones occurs in the subsurface, which implicates an overlooked contribution of “remote” electron sources/sinks for local biogeochemical processes.
