Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Wireless microwave-to-optical conversion via programmable metasurface without DC supply
By using battery-free programmable metasurface, the free-space microwave-laser conversion is realized for bidirectional air-water cross-media wireless communication.
Targeting Stem Cells in Medulloblastoma
Here, we tested the hypothesis that OLIG2, a key transcriptional regulator of neural development, plays a crucial role in maintaining cancer stem cells (CSC) in medulloblastoma tumors that can be exploited using a new type of targeted therapy.
Targeting Cell Fate Transitions in Medulloblastoma: Precision and Context Matter
Research from my lab led by Kinjal Desai, out today in Nature Communications, probes cell fate transitions in the medulloblastoma hierarchy. By blocking OLIG2, which drives the transition from quiescence to proliferation in the neoplastic stem cells, we block de novo tumour formation and regrowth.