Bacterially secreted amyloid fibrils were shown for the first time to catalyze the degradation of β-lactam antibiotics. This observation points to possible antibiotic resistance mechanisms associated with bacterial biofilms.
In a new study, we examine how global epistasis—where gene-gene interactions follow a tractable pattern—is shaped by the environment, and defines how drug resistance evolves in malaria. This may allow us to better predict and control adaptive evolution at the molecular level.
Adaptation of Staphylococcus aureus to the airways correlates with increased exploitation of metabolites released by the lung microbiota
Explore our Nature Communications study unraveling annelids' ancient secrets. We decode sterol evolution in animals’ ancient ancestor at the dawn of their evolution.
Influenza is not a single virus, but a collection of subtypes broken down into many different strains. Ordinary flu vaccines can only protect against a small proportion of these. Here, we obtained a surprisingly broad protection by sequential vaccination of pigs with highly diverse “H1N1” strains.