Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
De novo atomic protein structure modeling for cryoEM density maps
Cryo2Struct determines atomic structures of large proteins directly from cryo-EM density maps, advancing biomedical research and drug design.
The diverse functions of bacterial purine receptors
Bacteria rely largely on receptors to sense and respond to environmental signals. Different receptor families have evolved that regulate diverse processes like gene expression, metabolism, second messenger homeostasis, chemotaxis or virulence. However, the signals they recognise are mostly unknown.
Neutrons give a hot new way to measure the temperature of electronic components
Our modern world is full of temperature-sensitive electronic devices, and researchers led by Osaka University have developed a faster, highly accurate way to measure the temperatures of such devices using neutrons.
AAV-CXCL9 Combination Immunotherapy: A Promising Strategy in the Treatment of Glioblastoma
Investigators at the University of Florida Brain Tumor Immunotherapy Program developed a novel immunotherapy combining AAV gene therapy and anti-PD-1 immune checkpoint blockade to overcome immune suppression in glioblastoma.