Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Structure of human mitochondrial Mg2+ channel Mrs2
Mrs2 is a mitochondrial Mg2+ channel that is essential for metabolic function. We determined cryo-EM structures of human Mrs2 under different conditions, revealing a novel molecular mechanism of Mg2+ permeation through Mrs2.
Structure of human ZAC channel
ZAC is a Zn2+ and H⁺-activated cation channel and a critical target for neuropsychiatric drugs. we report the structures of human ZAC, providing insights into the gating and activation mechanisms of ZAC.
Modular synthesis of chiral 1,n-diols via photo/nickel co-catalysis
The Kong group developed a photo-HAT/nickel synergistic strategy for directly converting bulk chemicals like ethylene glycol and 1,3-propanediol into optically pure 1,2- and 1,3-diols. This method avoids toxic metal catalysts and complex precursors, enabling sustainable asymmetric synthesis.
