Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Extracellular vesicles, the rising stars in immunomodulation
In the past, most scholars think platelet-derived EVs are just the ashes from cells and had no idea about their functions. However, we are curious why activated platelets release so many EVs? We speculate that EVs may have holy missions during infection.
HPV circRNAs: Transformation with no end in sight
Although circular RNAs (circRNAs) are abundant and can be encoded by viruses, the function of most circRNAs remain unclear. We describe the discovery of circRNAs in human papillomaviruses (HPVs) including a circular E7 RNA (circE7). CircE7 is translated and required for transformation in cervical cancer cells, providing strong evidence that circRNAs can be translated and have important biological functions.
Jiawei Zhao
Richard Wang