Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
A tunable dual-input system for on-demand dynamic gene expression regulation
Dynamic gene expression patterns orchestrate cellular functions. To understand the link between dynamic behaviour and cellular phenotype, and to direct cell fate in a user-defined way, tools enabling precise tuning of gene activation levels and temporal dynamics were developed.
Gene therapy meets cell therapy in the fight for sight
In the eye, a tiny pit in the central retina provides us the clearest vision of all. This region contains the highest number of cone photoreceptors – responsible for our daylight, high acuity vision. Unfortunately, several diseases lead to the degeneration of these photoreceptor cells.
