Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Humans, sea slugs, kidney cells: we all learn the same way
Our new study shows that non-neural cells can count, tell time, and store complex information.
Making multispecific capacity of antibodies into a precision medicine tool
Behind the scenes of our work to adapt an agonistic antibody with any type of drug cargo in order for us to improve the impact on the immune system and thereby therapeutic efficacy.
Epigenetic modulation via the C-terminal tail of H2A.Z
The histone tail, as part of the endogenous H2A.Z, or added in excess to nuclei/cells, exerts a large effect on nucleosome stability as well as on nuclear architecture, and its alternative molecular engagements explain the intranuclear heterogeneity of the H2A.Z-nucleosomes in vivo.
One Stone, Two Birds: Detection and Understanding of Atmospheric Rivers
We use the same variable to detect and understand atmospheric rivers, killing two birds with one stone.
Highly efficient solar steam evaporation via elastic polymer covalent organic frameworks monolith
Elastic polymer covalent organic frameworks (PP-PEG) have been developed for efficient solar steam evaporation, which is expected to solve the problem of water scarcity.
The REZPEG Story
Impaired interleukin-2 production and regulatory T cell (Treg) dysfunction is implicated in multiple autoimmune diseases. Here, in two phase 1b trials, we show that rezpegaldesleukin, a Treg-selective pegylated IL-2, is safe and improves symptoms in patients with atopic dermatitis or psoriasis.