Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics
Bacterially secreted amyloid fibrils were shown for the first time to catalyze the degradation of β-lactam antibiotics. This observation points to possible antibiotic resistance mechanisms associated with bacterial biofilms.
“Effective interactions” shape the evolution of drug resistance (and much more)
In a new study, we examine how global epistasis—where gene-gene interactions follow a tractable pattern—is shaped by the environment, and defines how drug resistance evolves in malaria. This may allow us to better predict and control adaptive evolution at the molecular level.
When is a loss a gain? Decoding annelids dietary secrets ~630 million years ago
Explore our Nature Communications study unraveling annelids' ancient secrets. We decode sterol evolution in animals’ ancient ancestor at the dawn of their evolution.
An unconventional vaccination strategy against influenza viruses from humans and swine
Influenza is not a single virus, but a collection of subtypes broken down into many different strains. Ordinary flu vaccines can only protect against a small proportion of these. Here, we obtained a surprisingly broad protection by sequential vaccination of pigs with highly diverse “H1N1” strains.
