In late 2020 the COVID-19 vaccination rollout in England comprised two key recommendations: (i) prioritise elderly & vulnerable; (ii) interval between first & second doses increased from 3 to 12 weeks. We re-examined these recommendations with a mathematical model of SARS-CoV-2 infection in England.
Using genome structure, rather than gene trees, to infer relationships in ancient allopolyploid lineages
Many flowering plants are allopolyploids, meaning they arose from hybridization between different species, followed by genome doubling. Over time, gene trees for such lineages can become a hopeless tangle.