Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Pd-Catalyzed Asymmetric Allylic Pyridinylation Reaction under Electrochemical Conditions
By combining electricity and Pd catalysis, the first example of an asymmetric allylic pyrdinylation reaction was reported with 4-CN-pyridne as the pyridine source. The Pd catalyst acts not only as the transition-metal catalyst but also as an electron-transfer catalyst.
New Mechanism of Cross-scale Energy Transfer in Space Plasmas
Identifying energy transfer processes from macroscales down to microscales in collisionless plasmas is an indispensable step towards a complete understanding of various space and astrophysical systems. Here we demonstrate with observations that cross-scale wave-ion interactions are a candidate.
The establishment of a novel HB vaccine by using the yeast-derived large-HBs antigen.
Although the current HB vaccine comprising small-HBs antigen (Ag) is potent and safe, attenuated prophylaxis against hepatitis B virus (HBV) with vaccine-escape mutations has been reported. We established an HB vaccine consisting of large-HBsAg that overcomes the drawbacks of the current HB vaccine.