Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
EuMP cycle enable new gateway for one-carbon compound assimilation
In the pursuit of carbon-negative pathways for future biosynthesis, researchers are engaged in deconstructing natural pathways into modular components and reassembling them akin to assembling LEGO blocks. This work serves as an inspiration, highlighting the diversity inherent in natural enzymes.
DeepRTAlign: toward accurate retention time alignment for large cohort mass spectrometry data analysis
Retention time (RT) alignment is a crucial step in large cohort proteomics and metabolomics studies. Here, the authors introduce DeepRTAlign, a deep learning tool for RT alignment that shows high identification sensitivity and quantitative accuracy.
Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics
Bacterially secreted amyloid fibrils were shown for the first time to catalyze the degradation of β-lactam antibiotics. This observation points to possible antibiotic resistance mechanisms associated with bacterial biofilms.
