Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Either long-term grazing or long-term exclosure is not good grassland management strategy
Long-term grazing can disrupt the associations between plant biodiversity and ecosystem multifunctionality, while long-term exclosures may disrupt the associations between soil biodiversity and ecosystem multifunctionality, thus either is not good grassland management strategy.
Unraveling the Evolutionary History of Snake Toxins
Organisms poison each other for various reasons, making toxins a core component of the chemical ecology of many species. Some of these poisonous critters, including snakes, have a significant impact on human populations. Venture into the captivating world of snake toxins with us!
Diving into connections between the gut microbiota and host lipids
Correlations hint at connections between host traits and groups of bacteria from the gut microbiota, but the underlying mechanisms are often hard to figure out. We explored the biology of understudied gut bacteria from the genus Turicibacter and identified one way they are linked to host lipids.
Critical considerations of sensitivity and specificity for HIV reservoir measurements
The story behind our mathematical modeling study which took a deep dive into different assays for measuring the latent HIV reservoir, the barrier to cure.
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data
Multiplexed DNA fluorescence in situ hybridization (FISH) imaging technology has been developed to map the folding of chromatin fibers at tens of nanometers and several kilobases in resolution in single cells. We present SnapFISH to process the multiplexed DNA FISH data and identify chromatin loops.
Stem cell-like CD8 T cells are at the heart of the anti-tumor response induced by PD-L1/TGFβ dual blockade in immune excluded tumors
In depth analysis of the CD8 T cells infiltrating an immune excluded tumor model revealed the presence of stem cell-like CD8 T cells that expanded in situ upon anti-PD-L1/TGFβ combination therapy fueling an efficient and IFNγ dependent anti-tumor response.