Nature Methods
This journal is a forum for the publication of novel methods and significant improvements to tried-and-tested basic research techniques in the life sciences.
Ultraflat graphene membrane shapes uniform thin ice for cryo-EM analysis
Ultraflat graphene membrane is developed here as the supporting film for cryo-EM specimen preparation, which improves the image quality of vitrified samples and enables the high-resolution reconstruction of small macromolecules (<100KD).
Emu: a novel computational tool for more precise community profiles from full-length 16S sequences
Emu is a novel software designed to establish microbial community profiles with full-length 16S rRNA gene sequences from error-prone nanopore devices.
Describing the distribution of proteins on the cell surface
How can we quantify the nanoscale distribution of proteins on the cell surface? How can we tell if they are randomly distributed or not? The answer lies in a new data analysis method for single-molecule super-resolution microscopy.