npj Precision Oncology
An international, peer-reviewed journal committed to publishing cutting-edge scientific research in all aspects of precision oncology from basic science to translational applications to clinical medicine.
Deep learning-based microsatellite instability predictor from prostate cancer whole-slide images
Researchers developed a deep learning predictor of MSI in prostate cancer using a large, real-world cohort of H&E whole slide images. The screening algorithm may be used to rapidly prioritize patients for confirmatory testing, which can identify MSI-high patients who may qualify for immunotherapy.
Overcoming limitations in current measures of drug response may enable AI-driven precision oncology
State-of-the-art AI models in precision oncology were actually not giving personalized predictions 💣 Keep reading to learn how we discovered it ☄️
Are sex and gender adequately considered in head and neck cancer clinical studies?
Sex (male/female biological differences) and gender (differences related to men/women social behaviors) affect human health; yet, sex and gender variables are currently largely overlooked in head and neck cancer clinical studies, where they, instead, significantly influence cancer incidence.
Behind the Paper: “Molecular Disparities in Colorectal Cancers of White Americans, Alabama African Americans, and Oklahoma American Indians”
Hiroshi Y. Yamada, Upender Manne, Chinthalapally V. Rao
Advancing human and canine cancer care: analysis of the largest clinico-genomics canine cancer dataset as a hypothesis generation for cancer drug discovery
AI analysis of canine clinical and genomic data including treatment with targeted therapies can provide translational insights and help accelerate drug development and repurposing to improve cancer outcomes.