We show that Cntnap2 KO rats, a preclinical model for neurodevelopmental disorder, have intact startle scaling, but disrupted sound scaling in response to a prepulse, confirming that there are two independent scaling processes causing prepulse inhibition of startle.
POOR RESPONSE TO METHYLPHENIDATE IS ASSOCIATED WITH A SMALLER DORSAL ATTENTIVE NETWORK IN ADULT ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD).
The pathophysiology of neuropsychiatric disorders is a complex web of events and the biological processes involved are not fully understood. We have studied the levels of blood immune modulators in first episode psychotic patients revealing changes in EN-RAGE that is produced by neutrophils.
Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors
Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress
Development of the first Asian database of genome-wide DNA methylation correlations between brain and peripheral tissues of Japanese samples