Translational Psychiatry
This journal focuses on papers that directly study psychiatric disorders and bring new discovery into clinical practice.
Exploring SHANK3 in Neurodevelopment Using Stem Cells and Chemical Biology
Here we delve into our research on Phelan-McDermid syndrome (PMDS), a rare genetic disorder. We focused on SHANK3, an integral protein in neurodevelopment and synaptic function. We explore potential treatment strategies for PMDS, aiming to contribute to drug discovery in neurodevelopmental diseases.
Why rats (and humans) addicted to alcohol may not respond to psilocybin treatment
In our paper, we show how severity of alcohol relapse in rats can affect psilocybin’s mode of action
Prepulse inhibition of startle - Teaching a classic paradigm some new tricks
We show that Cntnap2 KO rats, a preclinical model for neurodevelopmental disorder, have intact startle scaling, but disrupted sound scaling in response to a prepulse, confirming that there are two independent scaling processes causing prepulse inhibition of startle.
