We show that Cntnap2 KO rats, a preclinical model for neurodevelopmental disorder, have intact startle scaling, but disrupted sound scaling in response to a prepulse, confirming that there are two independent scaling processes causing prepulse inhibition of startle.

Susanne Schmid and 1 other

Nov 29, 2023

Translational Psychiatry

Behind the Paper

What´s in blood ? EN-RAGE enters the stage

The pathophysiology of neuropsychiatric disorders is a complex web of events and the biological processes involved are not fully understood. We have studied the levels of blood immune modulators in first episode psychotic patients revealing changes in EN-RAGE that is produced by neutrophils.

Dan Lindholm

Oct 20, 2023

Research Communities by Springer Nature

Translational Psychiatry

Ketamine's antidepressant effects involve an evolutionarily ancient part of the brain

Prepulse inhibition of startle - Teaching a classic paradigm some new tricks

POOR RESPONSE TO METHYLPHENIDATE IS ASSOCIATED WITH A SMALLER DORSAL ATTENTIVE NETWORK IN ADULT ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD).

Exploratory evidence for differences in GABAergic regulation of auditory processing in Autism Spectrum Disorder

What´s in blood ? EN-RAGE enters the stage

Unexpected Gender Differences in Progressive Supranuclear Palsy Reveal Efficacy for Davunetide in Women

Preventing Post-Traumatic Stress Disorder (PTSD) in Rats with Pulsed 810 nm Laser Transcranial Phototherapy

Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors

Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations

A new approach to personalized treatments in addiction

Increased mortality in critically ill adults with mental disorders prescribing with selective serotonin reuptake inhibitors

Temporal dynamics in mental health symptoms and loneliness during the COVID-19 pandemic

The “Double Whammy”: When antidepressant resistance meets autoimmunity

The excitation/inhibition imbalance theory of autism: Linking genetics, brain structure and behavior

Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress

Development of the first Asian database of genome-wide DNA methylation correlations between brain and peripheral tissues of Japanese samples

Accelerated epigenetic aging in women with emotionally unstable personality disorder and a history of suicide attempts

Whole brain profiling of cocaine and sucrose processing in mice

Maternal preconception functionally suboptimal status of thiamine and child behavioural problems

Remember to sleep amid pandemics!

Translational Psychiatry

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