Peritumoural immunomodulatory scaffolds

A peritumourally implanted macroporous scaffold releasing small molecules and antibodies to suppress regulatory T cells and to attract and stimulate effector T cells enhanced endogenous antitumoural responses in mice bearing aggressive tumours.

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The cover illustrates that a scaffold releasing specific small molecules and antibodies can suppress regulatory T cells and attract and stimulate effector T cells when implanted peritumourally in mice.

See Majedi et al.

Image: Ella Marushchenko and Ekaterina Zvorykina, Ella Maru Studio, Inc. Cover design: Allen Beattie.

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Life Sciences > Biological Sciences > Biotechnology