Prime editing of pathogenic mutations in mouse eyes and livers
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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases - Nature Biomedical Engineering
In mouse models of hereditary tyrosinaemia and of Leber congenital amaurosis, prime editing can precisely correct the disease-causing mutations, ameliorating the disease phenotypes.
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Nature Biomedical Engineering
This journal aspires to become the most prominent publishing venue in biomedical engineering by bringing together the most important advances in the discipline, enhancing their visibility, and providing overviews of the state of the art in each field.