Stable transposon-driven integration of transgenes into immune cells

A gene-delivery system relying on a Sleeping Beauty transposase encoded into an mRNA delivered by an adeno-associated virus enhances the stability and efficiency of the integration and expression of a desired transgene in immune cells.
Published in Immunology
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The cover illustrates a gene-delivery system that enhances the stability of the integration of a desired transgene in immune cells by relying on a Sleeping Beauty transposase encoded into an mRNA delivered by an adeno-associated virus.

See Ye et al.

Image: Lupeng Ye and Sidi Chen. Cover design: Alex Wing.

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Immunotherapy
Life Sciences > Biological Sciences > Immunology > Immunotherapy