Antimicrobial resistance patterns of Streptococcus uberis isolates from bovine milk in Chiba prefecture, Japan: association between multidrug resistance and clonal complex 996

Published in Microbiology

Go to the profile of Takashi Takahashi
Takashi Takahashi
Professor, Kitasato University
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To provide treatment information for the mastitis caused by S. uberis in Japan, we aimed to clarify AMR patterns of the isolates from bovine milk mainly in Chiba. AMR phenotyping/genotyping [blaZ–erm(A)–erm(B)–mef(A)–linB–lnuD–tet(M)–tet(O)–tet(K)–tet(L)–tet(S)] and multilocus sequence typing were performed to analyze relationships between AMR patterns and clonal complexes (CCs). Resistance to tetracycline-, macrolide-, and lincosamide-classes was mainly associated with possession of tet(O), tet(S), erm(B), linB, and lnuD genes. CC996 was significantly associated with multidrug resistance (P <0.0001). These findings will aid Chiba farm animal clinics in treating bovine mastitis.

Go to the profile of Takashi Takahashi
Takashi Takahashi
Professor, Kitasato University

https://orcid.org/0000-0003-4131-2062

Researcher Name Resolver ID: 1000000292855

My Research Focus:
Characterization of virulence factors, epidemiological data, antimicrobial resistance patterns in Gram-positive cocci (genus Streptococcus and genus Staphylococcus) isolated from human patients and diseased companion animals

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Antimicrobial Resistance
Life Sciences > Biological Sciences > Microbiology > Medical Microbiology > Antimicrobials > Antimicrobial Resistance

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