The input parameters considered are Energy consumption (ENERGY), Vehicle Kilometers (VK), POPulation (POP), Year (Y), and Gross Domestic Product Per Capita (GDP). Strong correlations are observed, with ENERGY having the highest correlation followed by VK, POP, Y, and GDP. Four scenarios are designed based on the correlation effect: scenario 1 (ENERGY/VK/POP/Y/GDP), scenario 2 (ENERGY/VK/POP/Y), scenario 3 (ENERGY/VK/POP), and scenario 4 (ENERGY/VK). Experiments compare their effects on CO₂ emissions using statistical indicators (R², RMSE, MSE, and MAE). Across all scenarios and algorithms, R² values range from 0.8969 to 0.9886, and RMSE values range from 0.0333 to 0.1007. The XGBoost algorithm performs best in scenario 4. Artificial intelligence algorithms prove successful in estimating CO₂ emissions. This study has significant implications for policymakers and stakeholders. It highlights the need to review energy investments in transportation and implement regulations, restrictions, legislation, and obligations to reduce emissions. Artificial intelligence algorithms offer the potential for developing effective strategies. Policymakers can use these insights to prioritize sustainable energy investments. In conclusion, this study provides insights into the relationship between input parameters and CO₂ emissions in the transportation sector. It emphasizes the importance of proactive measures and policies to address the sector’s environmental impact. It also contributes to the understanding of AI-assisted CO₂ emissions forecasting in the transport sector, potentially informing future policy decisions aimed at emission reduction and sustainable transport development.