TRACERx: On the Cover

Research from the TRACERx consortium has provided the inspiration behind some recent journal covers.
Published in Cancer
TRACERx: On the Cover

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Nature Cancer
Volume 1 Issue 5, May 2020

Paper: The T cell differentiation landscape is shaped by tumour mutations in lung cancerTracing the effects of tumor mutations on T cell differentiation (Nature Cancer).

Behind the Paper: Coupling T cell differentiation to the lung cancer mutanome via neoantigen surveillance by James Reading.
Behind the Paper: Tumour neoantigens: the double edged sword that drives immune failure by Ehsan Ghorani.

Image: QuezadaLab, UCL Cancer Institute.
Cover design: Allen Beattie.

Nature Medicine
Volume 25 Issue 10, October 2019

Paper: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse (Nature Medicine).

Behind the Paper: Circulating tumour cells in the pulmonary vein of early stage non small cell lung cancer patients: what do they tell us about risk of relapse after surgery and seeding of metastasis? By Francesca Chemi. And video!

Image: Jeroen Claus.
Cover design: Erin Dewalt.

Volume 567 Issue 7749, 28 March 2019

Paper: Neoantigen-directed immune escape in lung cancer evolution (Nature).

Behind the Paper: Immune Sculpting of Cancer Evolution by Charles Swanton.

Image: Jeroen Claus/Phospho Biomedical Animation

TRACERx is a 9-year research programme which aims to integrate new technologies to understand the evolution of lung cancer - some of the latest findings are published today in a special collection by Nature.   

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