Go to the profile of Hagop Kantarjian

Hagop Kantarjian

Professor, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, MD Anderson Cancer Center, University of Texas
  • United States of America

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Leukemia
Behind the Paper

Five-year follow-up of OPTIC: long-term efficacy, safety, and mutation analyses of ponatinib in chronic-phase chronic myeloid leukemia from a randomized phase 2 trial

OPTIC was born from a clinical question about how best to balance efficacy and long-term treatment management with ponatinib. Five-year follow-up now shows how response-based dosing evolved from a hypothesis into a validated treatment strategy for patients with resistant chronic-phase CML.
Go to the profile of Hagop Kantarjian
Hagop Kantarjian
Jul 24, 2026

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Behind the Paper

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