Collection Overview
Scientific Reports has launched a Guest-Edited Collection on Brain metabolomics in dementia and neurological disease.
Brain metabolomics is a valuable tool for the study of dementia and other progressive neurodegenerative diseases with limited treatment options. Metabolite analysis in brain tissue and cerebrospinal fluid can identify changes in glucose metabolism, markers of oxidative stress and neurotransmitter disruption that may provide insight into disease mechanisms or act as diagnostic or prognostic indicators.
This will be a Collection of original research papers and will be open for submissions from all authors – on the condition that the manuscripts fall within the scope of the Collection and of Scientific Reports more generally. We are welcoming submissions until 21st May 2026.
Why is this Collection important?
"Understanding the molecular mechanisms of dementia and neurological diseases remains a major challenge in biomedicine. Brain metabolomics offers a unique window into these processes by capturing dynamic metabolic changes that reflect disease onset and progression. Linking molecular alterations to clinical outcomes bridges the gap between basic research and translational medicine, supporting biomarker discovery and early diagnosis.
This collection unites diverse perspectives from neuroscience, chemistry, and data-driven biology. Advances in NMR- and MS-based metabolomics, together with integrative omics and imaging approaches, are transforming how we study brain metabolism. By connecting molecular insights with in vivo magnetic resonance spectroscopy, we move closer to detecting and monitoring neurodegenerative diseases in patients.
Researchers should consider submitting to this collection because it provides a focused, interdisciplinary platform dedicated to metabolomics-driven insights into brain function and dysfunction. The collection welcomes both fundamental and applied research, encouraging dialogue between basic scientists, clinicians, and data analysts. Contributions here will not only reach a broad audience of metabolomics and neuroscience experts but will also help shape future directions in biomarker discovery, translational diagnostics, and therapeutic innovation.""
- Dr. Tobias Madl, Guest Editor
Why submit to a collection?
Collections like this one help promote high-quality science. They are led by Guest Editors, who are experts in their fields, and In-House Editors and are supported by a dedicated team of Commissioning Editors and Managing Editors at Springer Nature. Collection manuscripts typically see higher citations, downloads, and Altmetric scores and provide a one-stop-shop on a cutting-edge topic of interest.
Who is involved?
Guest Editors:
- Sarah Harris, The University of Edinburgh, United Kingdom
- Tobias Madl, Medical University of Graz, Austria
- Jacob Raber, Oregon Health & Science University, United States
- Laishram Rajendrakumar Singh, University of Delhi, India
Internal Team:
- In-House Editor: Claire Potter, Scientific Reports, UK
- Commissioning Editor: Ksenija Lindermane, Fully OA Brands, Springer Nature, UK
- Managing Editor: Anthony Heron, Fully OA Brands, Springer Nature, UK
How can I submit my paper?
Visit the Collection page for more information on the Collection, and how to submit your article.