Specifically, it investigates whether clots rich in red blood cells (RBCs) or those dominated by platelets and fibrin influence the likelihood of achieving first-pass recanalization (FPR)—a successful reopening of the blocked artery in a single attempt—and the risk of bleeding complications. While clot composition was not significantly linked to FPR success, it was strongly associated with the risk of intracranial hemorrhage. These findings suggest that clot histology could play a key role in predicting post-treatment complications, highlighting its potential clinical value beyond the known importance of achieving FPR.
Effect of thrombus composition on first pass recanalization and bleeding in acute ischemic stroke patients
This study aims to explore how the composition of blood clots affects treatment outcomes in patients with acute ischemic stroke undergoing mechanical thrombectomy.