Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
An unconventional vaccination strategy against influenza viruses from humans and swine
Influenza is not a single virus, but a collection of subtypes broken down into many different strains. Ordinary flu vaccines can only protect against a small proportion of these. Here, we obtained a surprisingly broad protection by sequential vaccination of pigs with highly diverse “H1N1” strains.
MultiPro: a comprehensive proteomic resource for investigation of multiple technical issues
Proteomics plays key roles in biomedical research but accompanied by technical issues like data integration, missing value imputation, batch effect correction and their confounding. To investigate these issues and benchmark data processing methods, proper gold standard proteomic datasets are needed.
Australia's Urban Evolution: Understanding Population, Climate, and Housing Dynamics
Urban areas worldwide are undergoing rapid population expansions, which drive not only economic growth but also lead to higher housing costs. In this paper, we propose a novel estimation approach to estimate the impact of population growth on housing costs using Australian city-level panel data.
Study of optimization for material processing parameters by means of probabilistic methodology for multi‑objective optimization
Selection and use of proper processing parameters are quite important for material machining.
In the present paper, the probabilistic methodology is employed to perform the designs of materials processing for improving quality and cost saving at the same time.
How many species are in your house?
Most ecologists are oblivious to the shockingly high biodiversity in front of their eyes every day. Our new paper explores the astonishing biodiversity in an urban Australian home - a house of a thousand species.
Quadrivalent self-amplifying mRNA vaccines generate protective antibody and cell-mediated immunity to influenza
Self-amplifying mRNA is a promising platform for vaccine development, highlighted by our group's recent publication in npj Vaccines showing that a quadrivalent bicistronic sa-mRNA vaccine can generate protective immunity to both HA and NA from 4 influenza strains when formulated in a single vaccine.
Wake slow waves in focal human epilepsy impact network activity and cognition
During sleep, slow waves carry a restorative function in normalizing neuronal excitability. Here, using intracranial recordings from patients with focal epilepsy, we provide evidence of a beneficial impact of wake slow waves against excitability associated with epileptiform discharges.
