Quadrivalent self-amplifying mRNA vaccines generate protective antibody and cell-mediated immunity to influenza
Self-amplifying mRNA is a promising platform for vaccine development, highlighted by our group's recent publication in npj Vaccines showing that a quadrivalent bicistronic sa-mRNA vaccine can generate protective immunity to both HA and NA from 4 influenza strains when formulated in a single vaccine.
During sleep, slow waves carry a restorative function in normalizing neuronal excitability. Here, using intracranial recordings from patients with focal epilepsy, we provide evidence of a beneficial impact of wake slow waves against excitability associated with epileptiform discharges.
Managing the legacy of historical drainage ditches in boreal peatlands: exploring the effect on water quality and greenhouse gas fluxes
The interplay between solar winds and planetary magnetic fields is pivotal for the evolution of planetary atmospheres and their habitability. Here we focus on how solar wind interacts with Mars.