Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Malaria genomic surveillance using nanopore sequencing: Shifting the focus into endemic countries
In this study, malaria parasite genetic surveillance was undertaken using targeted nanopore sequencing on portable MinION devices in Ghana. The end-to-end process, from sampling to sequencing to data analysis, was performed using laptop computers at two sites in Ghana, one urban and one rural.
“A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells”.
In this paper published in Cellullar & Molecular Immunology by Martín-Cruz L/Viñuela M et al (doi:10.1038/s41423-023-01096-6), we uncover novel molecular mechanisms by which heparan sulfate-related structures associated with tumor cells promote the generation of functional Tregs in cancer.
Rainfall is increasing on the edges of the South Asian Monsoon
Pakistan is a typical arid region where enhanced rainfall is more likely to cause floods. New research shows that the Middle East warming is increasing Pakistan's exposure to such disasters.
Direct time-resolved observation of surface-bound carbon dioxide radical anions on metallic nanocatalysts
A comprehensive understanding of the catalytic CO2 reduction mechanism has been limited by challenging direct time-resolved observation of the elementary steps. Here, we use pulse radiolysis to observe the stabilization processes towards well-defined nanoscale metallic sites.
