Future transition from forests to shrublands and grasslands in the western United States is expected to reduce carbon storage
Several computational methods have been developed to augment spatially resolved single-cell transcriptomics to measure more genes. We developed TISSUE to build on these methods by providing confidence in these computational measurements and additional tools for performing data analysis.
Computational modeling of radiation-induced lung fibrosis via the agent-based paradigm provides valuable insights into the initiation and progression of toxicity.
Contaminated landscapes – current use pesticides disperse from the valley bottom to the summit region
In this blog post Carsten Brühl from the institute for Environmental Sciences (iES) Landau at the RPTU in Germany is explaining the background of this first landscape level terrestrial pesticide exposure study.
Empowering Tomorrow's Cancer Specialists, the co-creation of the first Surgical Oncology Summerschool in Malawi
Cancer is a growing problem in Sub-Saharan Africa, with over 1 million new cases of cancer and over half a million cancer deaths annually. Treatment options are limited with surgery being the most valuable tool. Surgical training is limited, creating a need for additional education.
Second generation AR antagonists, abiraterone and enzalutamide, induce aberrant HGF/MET and Wnt pathways leading to increased XPO1 expression and ribosomal biosynthesis in double-null prostate cancer (DNPC). However, treatment with XPO1 and ribosomal inhibitors showed an improved antitumor response.
Studies show that standard preparedness measures do not predict COVID-19 outcomes, suggesting new measures are needed. But evaluating metrics is more than prediction. Measurement science points the way to tools that capture operational capabilities , including coordination and decisionmaking.
An intranasally administered chimeric protein antigen, rCTB-T2544, orchestrates the generation of extended milieu of protective antibodies and T cell responses in the intestine, fortifying anti-typhoidal immunity in mice.
Bridging the Gap: Potential Impact of Digital Health Interventions on Simultaneous Hypertension and Mental Health care
Hypertension and mental health challenges often co-occur but current care pathways lack simultaneous physical and mental health support. Here we describe the rationale for a feasibility RCT looking at the impact of a digital health tool (Holly Health) in a primary care setting.