Nature
A weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions.
The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence
Infections caused by Pseudomonas aeruginosa are difficult to threat for many reasons. Among them, P. aeruginosa shows intrinsic or acquired resistance to several antibiotics. It expresses virulence factors and adopts specific lifestyles, like biofilms, non-responsive to antibiotics.
