Nature Communications
An open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences.
Structure of human mitochondrial Mg2+ channel Mrs2
Mrs2 is a mitochondrial Mg2+ channel that is essential for metabolic function. We determined cryo-EM structures of human Mrs2 under different conditions, revealing a novel molecular mechanism of Mg2+ permeation through Mrs2.
Structure of human ZAC channel
ZAC is a Zn2+ and H⁺-activated cation channel and a critical target for neuropsychiatric drugs. we report the structures of human ZAC, providing insights into the gating and activation mechanisms of ZAC.
Modular synthesis of chiral 1,n-diols via photo/nickel co-catalysis
The Kong group developed a photo-HAT/nickel synergistic strategy for directly converting bulk chemicals like ethylene glycol and 1,3-propanediol into optically pure 1,2- and 1,3-diols. This method avoids toxic metal catalysts and complex precursors, enabling sustainable asymmetric synthesis.
The Visual Brain Is Tuned to Having Feelings About the World
How do our feelings emerge from what we see? Traditionally, feelings were thought to stem from recognizing objects or scenes. But could the brain directly sense emotion from basic visual processes like seeing colors and shapes? Our study delves into this intriguing question.