Investigating subcellular transcriptional programs in triple negative breast cancer cells
Gene expression programs are fundamental for the right maintenance of the cell, in fact they are known to be aberrant in cancer cells. Until now, gene expression programs have been investigated in a limited manner. This work aims to achieve a more detailed characterization of these programs.
A joint diffusion/collision model for crystal growth in pure liquid metals
In this paper, I proposed a joint diffusion/collision model to describe the growth kinetics of the liquid/solid interfaces for pure metals. This study resolved a long-standing
questions in solidification theory: Whether or not the growth is thermal activated in pure
liquid metals?
The NEREA Augmented Observatory: an integrative approach to marine coastal ecology
This post shares the story behind our recent Scientific Data paper, detailing the creation of the NEREA Augmented Observatory. Discover how we overcame challenges, innovated data collection, and collaborated to advance marine ecological research in the Gulf of Naples.
The missing intermediate to form ethanol from carbon dioxide
So far ethanol and ethylene have been suggested as twin products during CO2 electroreduction on copper. Here, via in situ surface-enhanced Raman spectroscopy and density functional theory, we report a specific intermediate for ethanol production, proposing an update reaction mechanism.
Photoreactive fragment pharmacophores explore potential binding sites and provide hits for highly challenging drug targets
Photoaffinity-tagged fragments are increasingly used for convenient hit detection and binding site mapping in early drug discovery. We tackled two important challenges by maximizing the pharmacophore diversity of the core fragments, and by enhancing the labelling efficiency of the photoaffinity tag.