Behind the Paper

The real stories behind the latest research papers, from conception to publication, the highs and the lows

Targeting fatty acid synthase in preclinical models of triple-negative breast cancer brain metastases synergizes with chemotherapy and impairs invasion

Metastatic triple-negative breast cancer cells need to acquire the ability to produce new fatty acids to more effectively colonize the brain. Our study investigates how this metabolic vulnerability can be targeted to increase efficacy of chemotherapies and impair cancer cell invasion.
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Nathan Merrill and 1 other
Jun 11, 2024