Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
The story behind a simple idea: rethinking headache care as a way to improve population health globally
In an era of changing landscape in global population health, improving the overall health of people suffering from headache disorders will be a feasible way to improve global population health.
Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma
Tracking down targets of the oncogenic epigenetic regulator C-terminal Binding Protein in a mouse pancreatic cancer (PDAC) model led us to ErbB3, highly expressed in up to 60% of PDAC, and the possibility for precision therapy in ErbB3+ PDAC using FDA-approved or novel anti-ErbB2/3 agents.