Molecular Psychiatry

This journal publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment, with emphasis on studies at the interface of pre-clinical and clinical research.

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Behind the paper: ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation

Surprisingly, dramatically different molecular pathways regulate adult neurogenesis in males and females. Importantly, these pathways are strongly impacted by the major autism/intellectual disability gene, ADNP and corrected by the ADNP neuroprotective site, the investigational drug davunetide.
Go to the profile of Illana Gozes
Dec 24, 2024