Behind the Paper

Modular Endoprosthesis vs. Cement Spacer After Proximal Humerus Tumor Resection — Do We Really Gain Functional Advantage?

Reconstruction following wide resection of proximal humeral tumors remains controversial. A comparative study was published in BMC Musculoskeletal Disorders.

Reconstruction following wide resection of proximal humeral tumors remains controversial. While modular endoprostheses are often considered the more “advanced” option, their cost and potential complications raise an important question:

Do they truly provide superior functional outcomes compared to cement spacers?

In our retrospective comparative study published in BMC Musculoskeletal Disorders, we evaluated outcomes in 58 patients who underwent limb-salvage surgery for proximal humerus tumors:

  • 19 patients reconstructed with modular endoprosthesis (humeral hemiarthroplasty)

  • 39 patients reconstructed with nail cement spacer

  

🔎 Key Findings

1.     Mean MSTS score:
 – Endoprosthesis: 24.8 ± 1.1
 – Cement spacer: 23.9 ± 1.4
        → Statistically significant difference (P = 0.018), but clinically modest

2.    Complication rates were comparable:
    – Endoprosthesis: 26.3%
    – Cement spacer: 28.2%

3.    No significant functional differences were observed in patients with or without axillary nerve or deltoid resection.

 

💡 Clinical Takeaway

Both modular endoprostheses and cement spacers provided durable limb-salvage reconstruction with nearly equivalent functional outcomes.

Importantly, our findings suggest no substantial added functional advantage of the more expensive modular endoprosthesis, particularly in settings where cost considerations are relevant.

This study supports thoughtful, individualized reconstructive decision-making based on:

  • Soft tissue status

  • Patient age and prognosis

  • Resource availability

  • Surgeon experience

 


📄 Outcomes of modular endoprosthesis reconstruction versus cement spacer reconstruction following resection of proximal humeral tumors
BMC Musculoskeletal Disorders (2022)
DOI: 10.1186/s12891-022-05432-4

Walid Atef Ebeid MD, Sherif Eldaw MD, Ismail Tawfeek Badr MD, Mohamed Kamal Mesregah MD, Bahaa Zakarya Hasan MD

Article links:

https://pubmed.ncbi.nlm.nih.gov/35597987/

https://link.springer.com/article/10.1186/s12891-022-05432-4

 


I would be interested to hear how others approach reconstruction after proximal humeral tumor resection:

  • Do you routinely favor endoprosthesis?

  • In which scenarios do you prefer cement spacers?

  • How heavily does cost influence your decision-making?