Leukemia
This journal publishes high quality, peer reviewed research that covers all aspects of the research and treatment of leukemia and allied diseases. Topics of interest include oncogenes, growth factors, stem cells, leukemia genomics, cell cycle, signal transduction and molecular targets for therapy.
Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL
The detailed functional study of rare and unusual genomic events in patient cancer samples can provide some unique and important biological insights. We have uncovered a novel mechanism of tyrosine kinase activation in a form of leukaemia in which tyrosine kinase activation is the hallmark.
A novel, combined leukemic and infection model to study the antigen-specific T cell response in the context of chronic lymphocytic leukemia
The authors have set-up a novel murine model to study CLL-induced T-cell dysfunction.
Conditioning intensity matters for allogeneic stem cell transplantation in blastic plasmacytoid dendritic cell neoplasm
Using the European Society for Blood and Marrow Transplantation ProMISe databank, we found myeloablative induction therapy and total body irradiation to be the main determinants of long-term response to allogeneic stem cell transplantation in blastic plasmacytoid dendritic cell neoplasm.