Nature Biotechnology
A monthly journal covering the science and business of biotechnology, with new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences.
Selecting the most appropriate SpCas9 variants for your own interests
Among the numerous SpCas9 variants that previously reported, we compared 13 variants to provide guidance to researchers. We developed a computational tool that predicts the activities of the variants to provide insights in selecting the most appropriate variants for their own research purposes.
Improving the versatility of CRISPR genome editing using a hybrid approach. By Jason Moffat
CHyMErA - a new CRISPR-based tool allows simultaneous genome editing at multiple sites to learn how different genomic sites and DNA stretches co-operate in health and disease.